Research Lab Manager, Infectious Disease

About This Role

Manage the infectious disease research lab under Dr. Pritha Sen at Brigham and Women's Hospital, focusing on single-cell and nuclei RNA sequencing protocols for human immunology studies. The role supports ongoing projects to understand viral immunity and immunopathogenesis in immunocompromised hosts.

Responsibilities

• Supervise and/or implement wet-bench single-cell and sequencing operations
• Oversee supply inventory related to high-dimensional immunophenotyping and sequencing
• Process clinical human blood and tissue specimens for single-cell and sequencing workflows
• Participate in the design and modification of single-cell, sequencing, and immunophenotyping research protocols
• Participate in the maintenance of specialized equipment for experimental workflows
• Develop research methodologies within experimental protocols and research objectives
• Perform data analysis using advanced statistical techniques
• Contribute to writing sections of research reports and manuscripts
• Oversee and coordinate all lab activities, including quality assurance and scheduling
• Troubleshoot problems and instruct others in highly specialized techniques

Requirements

• Minimum 3 years of experience in an academic and/or laboratory research setting
• Minimum 1 year of experience executing emulsion-based single-cell/nuclei library generation and next-generation sequencing workflows
• Highly organized, meticulous, and rigorous in wet bench experimental protocols
• Ability to make independent decisions
• Aptitude for technical problem solving
• Ability to effectively supervise others
• Excellent organizational skills
• Strong budget and management skills
• Excellent judgement and ability to interpret information
• Interest and comfort with working with human clinical specimens
• Computer literacy with Microsoft Word, Excel, PowerPoint
• Ability to record and analyze data using basic statistics
• Ability to perform a variety of routine tests and prioritize work
• Outstanding interpersonal and communication skills
• Highest levels of professionalism

Qualifications

• Bachelor's Degree Related Field of Study required. Specialized training in genomics and or immunology would be considered favorably.
• Minimum 3 years of experience in an academic and/or laboratory research setting AND at least 1 year of experience in executing emulsion-based single-cell/nuclei library generation and next-generation sequencing workflows.

Nice to Have

• Specialized training in genomics
• Specialized training in immunology
• Willingness to learn Adobe Illustrator
• Willingness to learn reference managers (e.g., Zotero)

Skills

* Required skills