Senior Clinical Project Manager – Oncology/Hematology (Phase III)

About This Role

Lead and manage complex global Phase III oncology and hematology clinical trials, driving operational and financial success while leading cross-functional teams and mentoring junior project managers.

Responsibilities

• Drive the operational and financial success of Phase III clinical trials
• Lead cross-functional teams across Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and QA
• Act as the primary liaison with clients, ensuring smooth project launch, conduct, and closeout
• Oversee project deliverables, timelines, and budgets while proactively identifying and mitigating risks
• Mentor junior project managers and project support staff, fostering collaboration and professional growth
• Own project budgets, forecasts, and financial performance
• Ensure alignment and accountability across all vendors and study partners
• Implement contingency plans and risk mitigation strategies to keep projects on track
• Support inspection readiness and Trial Master File compliance
• Participate in bid defense meetings as the potential project lead

Requirements

• Experienced Global Project Leader (NA, LATAM, EMEA, and APAC) with strong Phase III CRO project management experience
• Oncology and Hematology expertise, with direct experience leading complex Phase III trials
• Cross-functional team leadership (Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and Quality Assurance)
• Financially savvy, skilled in managing multi-million-dollar budgets (creation, forecasting, negotiation of out-of-scope work)
• Vendor management expertise
• Deep regulatory knowledge, with expertise in GCP/ICH guidelines and other applicable regulatory requirements
• Educational foundation: Bachelor’s degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related field

Qualifications

• Bachelor’s degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related field
• Seasoned CRO project leader with expertise in oncology and hematology research, proven track record of delivering clinical trials successfully, and experience managing multi-million-dollar budgets.

Benefits