LC-MS Scientist

About This Role

Perform LC and LC-MS based analyses to support analytical development and manufacturing activities, with a strong focus on accuracy and rapid turnaround. Optimize analytical methods and provide scientific support for ongoing innovations.

Responsibilities

• Perform LC and LC-MS based analyses to support analytical development, DS/DP development, and manufacturing activities
• Conduct failure sequence analysis, deamination analysis, residual mesyl azide quantification, oligonucleotide purity/impurity profiling, and unknown impurities identification
• Deliver and document results with a strong focus on accuracy and rapid turnaround
• Optimize analytical methods under guidance of supplier supervision
• Conduct feasibility assessments and provide scientific support for ongoing innovations
• Process, interpret raw data and properly document results
• Communicate any issues or concerns related to equipment, testing methods, or samples, and actively support troubleshooting and resolution efforts
• Ensure efficient sample testing by daily check and preparation of instrument, method setup, material and solution preparation, and maintaining a well-organized laboratory environment
• Support sample testing and logistics, including shipping and receiving samples among sites and facilities

Requirements

• Minimum of a BS with 3-4 years of relevant experience in pharmaceutical or biotech setting
• Authorization to work in the United States indefinitely without restrictions or sponsorship
• Experience in the design and execution of analytical chemistry laboratory experiments
• Good understanding of analytical method development
• Strong knowledge and hands on experience in LC- and LC/MS- based analysis

Qualifications

• BS degree
• 3-4 years of relevant experience in pharmaceutical or biotech setting

Nice to Have

• Prior knowledge and experience in oligonucleotide analysis
• Familiarity with data software such as Chemstation, OpenLab, WatersConnect, Xcalibar

Skills

* Required skills

Benefits