Senior Research Scientist

About This Role

Lead assay development efforts focused on NGS technologies, including single-cell RNA-seq and whole genome sequencing to create innovative diagnostic and therapeutic products for precision oncology. This role translates early research concepts into clinical assays, enhancing immunotherapy treatment decision-making.

Responsibilities

• Design, develop, and optimize molecular assays for diagnostic applications with a focus on immune characterization and an emphasis on single-cell RNA-based solutions
• Contribute to development and optimization of NGS workflows, including library preparation, sample processing, and quality control
• Evaluate and implement new technologies, reagents, and platforms to improve assay performance, robustness, and scalability
• Plan and execute experiments independently, analyze data, and clearly communicate results to internal stakeholders
• Collaborate closely with the R&D and computational biology teams to ensure seamless integration of wet-lab and analytical workflows
• Develop and document standard operating procedures (SOPs), protocols, and technical reports suitable for regulated environments
• Mentor junior scientists and contribute to building best practices within the R&D organization
• Support technology transfer from R&D into product development and clinical operations as needed

Requirements

• PhD or BS/MSc with significant industry experience in molecular biology, biochemistry, genetics, bioengineering, or related field
• 5+ years of hands-on laboratory experience in molecular biology and assay development
• Deep expertise with single-cell RNA-seq technologies (e.g. scRNA-seq, scWGS, scATAC-seq, scMultiomics)
• Deep expertise in NGS technologies, including library prep, sequencing platforms, and workflow optimization
• Strong experimental design, troubleshooting, and data interpretation skills
• Demonstrated success working with cross-functional, fast-moving research or startup environments and collaborating with computational scientists
• Outstanding written and verbal communication skills
• Ability to handle several fast-paced projects concurrently
• Demonstrated curiosity and scientific rigor with excellent problem-solving skills
• Ability to engage in crucial conversations – providing and receiving feedback

Qualifications

• PhD (or BS/MSc with significant industry experience) in molecular biology, biochemistry, genetics, bioengineering, or a related field
• 5+ years of hands-on laboratory experience in molecular biology and assay development

Nice to Have

• Solid working knowledge of immunology, particularly as it relates to immune-cell phenotyping
• Background in immunology, immuno-oncology, or immune-mediated diseases
• Experience developing assays intended for clinical or regulated use (e.g., CLIA, CAP, or FDA-regulated environments)
• Familiarity with computational methods for analysis of single-cell and other NGS data, especially for quality control
• Prior experience bringing assays from early research through to product development
• Experience with automation of cell and molecular biology assays, especially sample extraction and NGS library preparation

Skills

* Required skills

Benefits