Discovery Synthesis & Purification Co-op

About This Role

Wave Life Sciences is seeking a highly motivated co-op student to join its team of scientists in Lexington, Massachusetts. This co-op student will gain exposure to areas of oligonucleotide synthesis, formulation, purification, and analysis. This is an excellent learning opportunity for future entrance into industry or academia.

Responsibilities

• Perform downstream processing of oligonucleotides synthesized at various scales, utilizing various purification modalities, but specifically Anion Exchange (AEX) chromatography and size exclusion chromatography (SEC).
• Learn the AKTA Unicorn software to assist in developing new methods/gradients
• Characterize compounds using analytical instrumentation i.e., UV, pH, UPLC and LC-MS
• Operate and maintain lab equipment such as synthesizers, ÄKTA purifiers, UPLC, LC-MS, Nanodrop, and other analytical instrumentation
• Maintain timely, detailed written and electronic records of experimental protocols and data in accordance with company policy
• Potential to learn synthesis of oligonucleotides on the MM12, MM192 and AKTA synthesis systems if timing allows

Requirements

• Strong organizational skills
• Attention to detail
• Completion of coursework in organic chemistry, biochemistry, analytical chemistry with laboratory experience

Qualifications

• coursework in organic chemistry, biochemistry, analytical chemistry with laboratory experience

Skills

* Required skills