Director, Business Strategy & Operations - Commercialization

About This Role

This role will lead business strategy and operations for commercialization at Dyne Therapeutics, driving clarity, alignment, and executional excellence as the company transitions to commercial launch across multiple therapy areas. The Director will partner with the Chief Commercial Officer to translate strategy into actionable plans and lead high-priority, cross-functional initiatives.

Responsibilities

• Partner closely with the CCO to translate commercial strategy and priorities into actionable and measurable plans, ensuring clarity, structure, and consistency across initiatives
• Establish and manage the operating rhythm for the Commercial organization, including leadership forums, governance processes, decision-focused meetings, and business reviews that drive alignment and follow-through
• Lead and coordinate high-priority, cross-functional initiatives essential to commercial readiness, serving as the central connector between Commercial and partner functions with clear roles, responsibilities, and timelines
• Develop and deliver high-quality executive materials, including Board updates, enterprise presentations, town hall content, and cross-functional communications in partnership with Corporate Affairs
• Support preparation and coordination for the CCO’s engagement with key external stakeholders, such as KOLs, HCPs, patient advocacy groups, strategic partners, and internal senior leaders
• Drive operational excellence through OKRs (objectives and key results for the CCO team), dashboards, performance tracking, and business review processes
• Promote alignment, communication, and collaboration across Commercial and partner functions to ensure connectivity between strategy and execution
• Help strengthen Commercial team culture by reinforcing collaboration, accountability, and clear communication as the organization grows and prepares for launch

Requirements

• 10+ years of progressive experience in biotechnology or pharmaceuticals
• Experience supporting at least two successful rare disease product launches in a commercial, strategic, or operational leadership capacity
• Strong cross-functional leadership experience in high-growth, dynamic environments
• Exceptional communication, organization, and influencing skills

Qualifications

• Bachelor’s degree required; advanced degree (MBA, PharmD, PhD) preferred
• 10+ years of progressive experience in biotechnology or pharmaceuticals

Nice to Have

• Advanced degree (MBA, PharmD, PhD)