Biochemist II - Conjugation

About This Role

Perform precise antibody–fluorophore conjugations, from small-scale development to large-scale production, ensuring high technical proficiency, consistent execution, and excellent documentation practices to support continuous improvement and future-ready operations.

Responsibilities

• Perform antibody–dye conjugations across scales; protect light‑sensitive fluorophores during reaction and purification
• Purify conjugates via SEC, desalting, and/or affinity chromatography
• Calculate concentrations, D/P ratios, yields, and other key quality metrics
• Drive yield and passing rate improvements
• Operate, maintain, and troubleshoot lab equipment
• Support semi‑automated instrumentation and electronic batch records
• Support adoption of automation and AI‑enabled tools that enhance accuracy and efficiency
• Review, verify, and update SOPs, batch records, and compliance documentation
• Participate in troubleshooting, root-cause investigations, and continuous improvement and lab safety initiatives
• Provide training to team members

Requirements

• Bachelor’s degree in Biochemistry, Chemistry, or related field
• 2+ years of independent, hands‑on experience performing high‑quality antibody–dye conjugation reactions

Qualifications

• Bachelor’s degree in Biochemistry, Chemistry, or related field
• 2+ years of independent, hands‑on experience performing high‑quality antibody–dye conjugation reactions

Nice to Have

• Strong understanding of conjugation chemistry and purification techniques
• Experience handling light‑sensitive fluorophores during reaction and purification while maintaining product integrity
• Experience with multiple conjugation chemistries
• Exposure to automation, SEC, and electronic batch records
• Experienced in manufacturing under ISO/GMP environment

Skills

* Required skills

Benefits